Clinical and Radiologic Features of Fulminant Pediatric Autoimmune Encephalitis: A Case Report

doi:https://doi.org/10.21980/J8JW75

Clinical and Radiologic Features of Fulminant Pediatric Autoimmune Encephalitis: A Case Report

Raymen Rammy Assaf, MD, MPH^{*^}

^*Harbor UCLA Medical Center, Department of Pediatric Emergency Medicine, Torrance, CA

^{^}Children’s Hospital of Orange County, Emergency Medicine Specialists of Orange County, Orange, CA

Correspondence should be addressed to Raymen Rammy Assaf, MD, MPH at rassaf@emsoc.net

DOI: https://doi.org/10.21980/J8JW75 Issue 7:2

Infectious Disease Pediatrics Visual EM

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ABSTRACT:

There is a growing body of literature and scientific discovery on pediatric autoimmune encephalitides. This is a heterogenous group of neuroinflammatory conditions leading to often perplexing acute and progressive neurologic and/or neuropsychiatric symptoms. This report demonstrates the evaluation and management of an adolescent with myelin-oligodendrocyte glycoprotein (MOG) antibody-associated fulminant acute disseminated encephalomyelitis (ADEM) in the context of current literature. The featured magnetic resonance imaging uniquely highlights progressive central nervous system lesions detected over the course of the first week of disease.