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A Case Report of Calciphylaxis

Kim Hoang, BS*, Tien Lu, MD^, Alex Dang, MD^, Danielle Matonis, MD^

*University of California, Irvine, School of Medicine, Irvine, CA
^University of California, Irvine Health, Department of Emergency Medicine, Orange, CA

Correspondence should be addressed to Danielle Matonis, MD at dmatonis@hs.uci.edu

DOI: https://doi.org/10.21980/J8KW8V Issue 10:3
Visual EMDermatologyInfectious DiseaseRenal/Electrolytes
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Calciphylaxis Photo LLE. JETem 2025 1
Calciphylaxis Photo RLE. JETem 2025

ABSTRACT:

Calciphylaxis is a rare condition that is not well understood but is known to carry significant morbidity and mortality. We present a 44-year-old male with a history of end-stage renal disease on dialysis complaining of increasingly painful chronic wounds. The patient’s physical exam was remarkable for ulcerated, bilateral anterior leg wounds with large areas of eschar along with purulent drainage. He was admitted to the hospital for intravenous antibiotics, wound care, and specialist consultation for treatment of calciphylaxis. This case report provides an overview of the key clinical features of calciphylaxis and reviews potential treatment strategies for this life-threatening condition.  

Topics:

Calciphylaxis, chronic kidney disease, end-stage renal disease, wound infection, wound care.

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Issue 10:3

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